Doctor's Data offers scores of distinct tests across key categories:
Allergy & Immunology
Clinical Microbiology

Environmental Exposure/Detoxification
Toxic & Essential Elements

GI Pathogen Profile, multiplex PCR
Identifying Gastrointestinal Viruses, Parasites and Bacteria

The Centers for Disease Control estimates that 350 million acute diarrheal illnesses occur annually, and notes that diarrheal syndromes are often similar in presentation. Practitioners frequently encounter complex cases in which co-infections result in the difficult task of identifying the specific cause(s) of the symptoms of acute, or more devastating, chronic illness. Historically, the lack of testing methods that could identify a full range of viruses, parasites, and bacteria has made some GI infections difficult to diagnose – Doctor’s Data now offers a more comprehensive, accurate and rapid solution.

Doctor’s Data has become the leader in world class microbial analysis and gastrointestinal health using state of the science technology and methodologies. The GI Pathogen Profile, employing multiplex PCR technology is the newest test available within our arsenal of clinical Microbiology profiles.

The GI Pathogen Profile, multiplex PCR from Doctor’s Data is capable of the simultaneous detection and identification of 22 specific gastrointestinal pathogenic microbes using FDA-cleared*, multiplex FilmArray PCR technology with up to 98.5% overall sensitivity and 99.3% overall specificity. The identification of the pathogenic viruses, parasites, and bacteria along with a rapid-turnaround time of 24-48 hours significantly expedites clinical decisions and treatment options.
The following bacteria (including several diarrheagenic E. coli/Shigella pathotypes), parasites, and viruses are identified using the GI Pathogen Profile: 
Campylocbacter (C. jejuni/C. upsaliensis)
Clostridium difficile
(toxin A/B)
Pleasiomonas shigelloides
Vibrio (parahemolyticus, vulnificus, cholerae)
Vibrio cholerae
Yersinia enterocolitica

Adenovirus F 40/41
Norovirus GI/GII
Rotavirus A
Sapovirus (I, II, IV, and V)
Diarrheagenic E. coli/Shigella
E. coli O157
Enteroaggregative E. coli (EAEC)
Enteropathogenic E. coli (EPEC)
Enterotoxigenic E. coli (ETEC) lt/st
Shiga-like toxin-producing E. coli (STEC) stx1/stx2
Shigella/Enteroinvasive E. coli (EIEC)
Cyclospora cayetanesis
Entamoeba histolytica
Giardia duodenalis
(aka lamblia & intestinalis)

  Click here for a full sample report
*Currently, validated FDA-cleared probes exist only for pathogenic species. The use of probes in diagnostic assays that have not been validated or cleared by the FDA may decrease the accuracy of results.
Patient populations that may especially benefit from the comprehensive testing offered by the GI Pathogen Profile include:

  • Chronic or acute diarrhea
  • Bloody stool
  • Travelers diarrhea
  • Abdominal Pain
  • Fever & vomiting
  • Immuno-compromised patients
  • Geriatric Patients
  • Chronic disease patients (heart disease, aortic grafts, diabetes, chronic renal disease)
  • Observed cluster or suspected outbreak of diarrheal illness
Not all pathogenic microbes require antimicrobial treatment and such agents have no effect on viral infections. Certain pathogenic bacterial and parasitic infections call for rehydration and supportive therapies while others require antimicrobial treatment. Knowing the difference reduces the unnecessary use of antibiotics that may disrupt the microbiome, increase bacteria resistance, and the risk of complications and side effects associated with inappropriate use of antimicrobial agents. The test facilitates therapeutic efficacy.
Virus Detection
Viral infections are the predominant cause of acute diarrheal illness and are the least commonly tested. In fact, Norovirus is the primary GI infection occurring in the United States today. Practitioners have long awaited reliable molecular detection of GI viruses. The GI Pathogen Profile now makes this possible and may substantially improve patient outcomes and clinical success.
Consider a Comprehensive Stool Analysis
While the GI Pathogen Profile offers a targeted analysis for 22 known pathogenic microbes that are associated with gastrointestinal illness, co-infection of multiple organisms can occur. Additional stool testing may be valuable to further investigate organisms not included in the test that may play a role in the cause of symptoms and/or disease. Practitioners can look to the Comprehensive Stool Analysis w/ Parasitology profile from Doctor's Data for the identification and susceptibility of other bacteria, yeast, and parasites that may be contributing factors in such cases.
If your patient suffers from diarrheal illness, fast and accurate results are crucial. Consider the GI Pathogen Profile, multiplex PCR from Doctor's Data to aid in the rapid and precise identification of known pathogens that can cause serious patient morbidity.
Do you have questions about this or any of our other tests? Click the button below to complete our contact request form and your territory representative will reach out to you shortly.

Follow links below to view other suggested Doctor's Data Profiles:

Want to see the latest research on this topic?
Herikstad, H. et al. A population-based estimate of the burden of diarrehoeal illness in the United States: FoodNet, 1996-7. Epidemiology and Infection 129, 9-17 (2002).
Center for Food Safety and Applied Nutrition (U.S.) The bad bug book: foodborne pathogenic microorganisms and natural toxins handbook. (International medical Pub., 2004).
Glass RI, Parashar U, Estes M. Nororvirus Gastroenteritis. N Engl J Med. 2009 October 29; 361(18).
Nelson A et al. Disruption of the Human Gut Microbiota following Norovirus Infection. PLosOne 7(10):e48224.

Why Choose Doctor's Data, Inc?
Doctor's Data, Inc. has provided innovative specialty testing to healthcare practitioners around the world from our advanced CLIA-licensed clinical laboratory since 1972.
A specialist and pioneer in essential and toxic elemental testing, the laboratory provides a wide array of functional testing to aid in decision making and better patient outcomes.  Choose DDI to help you assess and treat heavy metal burden, nutritional deficiencies, gastrointestinal function, cardiovascular risk, liver and metabolic abnormalities, hormone status, and more.