MALDI-TOF and Stool Analysis -
Experience Matters

Experience Matters
It is true that imitation is the sincerest form of flattery. Recently, a few labs in the functional medicine industry have followed suit and acquired the MALDI-TOF technology as a portion of their stool analysis platform. This is truly a testament to DDI's early recognition of its potential in exploring the gut microbiome. However, it must be noted that all MALDI-TOF technology is not created equal. It is of the utmost importance that clinicians understand that experience matters when it comes to such sophisticated technology.


Here at Doctor's Data, we are truly grateful for the feedback and testimonials that you have shared over the past year regarding the specificity of our GI assessment profiles. Today, we briefly highlight what sets Doctor's Data apart from other stool analysis technologies and also explain why you should always look for our MALDI-TOF logo on your test result.
Bacteria Identification
Unlike publicly available sequence databases such as GenBank, MALDI-TOF Mass-Spectrometry databases are proprietary. Therefore, the size of the reference database is a key component to determining the depth of microbial identification that MALDI-TOF can provide. Doctor's Data uses an expanded, open reference library that allows us to successfully identify over 1,200 bacteria, including 84 Clostridium spp for our Comprehensive Clostridium Culture. Our comprehensive library also allows us to identify underreported enteric pathogens such as Arcobacter spp and Laribacter hongkongensis (see image below).
Yeast Identification
Yeast differentiation requires a much more skilled culture technique and can sometimes create difficulties when labs are trying to identify multiple yeast species. Our expertise with MALDI-TOF has helped us to identify over 180 different yeast species to date, including 65 Candida species. As a result, our yeast reports are not limited to one or two species, such as Candida albicans versus Candida not albicans. We are CLIA certified for high-complexity culture; our unique ability to differentiate yeasts in a single sample is important as some of your patients may have upwards of 6-7 different yeast from multiple genera (Candida, Cryptococcus, Debaryomyces, Exophiala, Saccharomyces, Udeniomyces, Zygosaccharomyces, just to name a few).
Doctor's Data is an Active Contributor Towards Tomorrow's Gut Microbiome

Doctor's Data uses the most expansive MALDI-TOF reference database available and it is currently growing by about 100 species per month. We also contribute to the database by submitting unidentified bacteria that we find in your patient samples for sequencing and validation. Once the species has been validated, we begin reporting these novel gut microorganisms in future patient reports.
We Go the Extra Mile in Our Parasitology Analysis
Many of you have inquired about our method of parasite identification. Doctor's Data uses gold standard O&P microscopy along with EIA (Enzyme Immunoassay). Where we might differ from other labs is in our analysis of multiple parasitology specimens or Parasitology x3 profiles. Although more labor intensive, Doctor's Data examines multiple slides for each sample submitted (a total of 6 slides for a Parasitology x3 profile). Literature has shown that this method provides slightly better results with certain types of parasites. For this reason, we choose not to pool multiple parasitology samples into one prior to analysis. As our reports state: One negative specimen does not rule out the possibility of parasitic infection, Parasitology x3 recommended.

Follow links below to view Doctor's Data profiles that utilize MALDI-TOF Detection 

    Why Choose Doctor's Data, Inc.?


    Doctor's Data, Inc. has provided innovative specialty testing to healthcare practitioners around the world from our advanced CLIA licensed clinical laboratory since 1972.

    A specialist and pioneer in essential and toxic elemental testing, the laboratory provides a wide array of functional testing to aide in decision making and better patient outcomes. Choose DDI to help you assess and treat heavy metal burden, nutritional deficiencies, gastrointestinal function, cardiovascular risk, liver and metabolic abnormalities, and more.

    ęDOCTORS DATA, INC. | 3755 Illinois Avenue, St. Charles, IL 60174-2420 USA | 800.323.2784 (US and Canada) | 0871.218.0052 (UK) | +1.630.377.8139 (Global) | +1.630.587.7860 (Fax)