Doctor's Data and Labrix teams have joined forces to produce educational content for providers. 

 

Registration Open!

Laboratory, Endocrine, & Neurotransmitter Symposium

October 4 - 6, 2019

Portland, OR

Earn up to 14.5 CME credits!

Gain additional clinical insight and treatment considerations to evaluate some of the most prevalent and challenging conditions that patients present with, including depression, anxiety, altered mental focus and stamina, sexual dysfunction, sleep disturbances, addictions and dependencies, weight management, and chronic disease. Register now to get the early bird price of $329 (reg. $379).

 

Wellness Wednesday

Webinar Series

Topic: Neurotransmitter Primer

By: Laura Neville, ND

June 5, 2019

Join our clinical staff and special guests on the first Wednesday of every month at 9:30 AM and 12:00 PM PST. This free, live webinar series will cover a variety of neuro-endocrine topics that will enhance your knowledge, with clinically applicable testing and treatment considerations. 1 CE credit available upon attendee request.

IFM (AIC)

San Antonio, TX:

May 30 - June 1, 2019

Make sure to visit our booth at IFM (AIC) in San Antonio this weekend. Chat with our booth representatives to learn what's new.

 

IFM (APM)

Denver, CO:

July 18 - 23, 2019

We will be in Denver for IFM (APM) on July 18-23. Don't miss our lunch presentation on hormones by Brandon Lundell, DC on July 18.

 

The Green Drink Conundrum:

Potential Thallium Exposure and Neurological Risks

 

By Julia Malkowki, ND, DC | May 29, 2019

Thallium (Tl) is a highly toxic heavy metal that has no physiological function. More toxic to humans than mercury, cadmium or lead, Tl is increasingly prevalent in the environment partly as a result of modern industrial practices and crop irrigation. Vegetables most heavily contaminated with Tl are the Spinacia and Brassica groups inclusive of spinach, kale and lettuces. Direct sources of exposure include cement dust, combustion of some types of coal and leakage of fracking wastewater from legal and illegal storage pits and wells. Unfortunately there is a man-induced omnipresence of yet another toxic metal that has great potential to diminish health and well-being. 

Thallium elicits neurotoxic effects as it inhibits DNA and protein synthesis, binds sulfhydryl groups on proteins of neurons and mitochondria, impairs the production of ATP, and competes with potassium. Thallium accumulates in the tissues with high potassium content such as skeletal and cardiac muscle, and the central and peripheral nervous systems. Thallium toxicity may manifest as alopecia areata, fatigue, headaches, depression, sleeplessness, ataxia, neuropathy, vision disturbances, psychoses, gastric antacidity, loss of appetite and/or weight, cardiac arrhythmias, angina-like pain, hypertension and irregular pulse. Thallium is primarily excreted via the kidneys and secondarily in bile. It may be found in urine as long as two months after exposure. Urine levels are an appropriate measure of Tl exposure and possible body burden.

The greatest exposure to thallium is from food, although exposure from air and water may occur from industrial operations. Smokers have been shown to have twice as much Tl exposure than non-smokers. In 1972 Tl-containing rat poison was discontinued due to the risk to human health. Current irrigation practices permit the use of fracking wastewater for irrigation of crops such as vegetables and fruit. An Environmental Working Group report found that 95,000 acres of produce in California was irrigated with fracking wastewater brine. Analyses of surface stream water near a fracking site indicated significant Tl contamination. Spinacia and Brassica group vegetables, such as kale, cabbage, spinach and lettuce, efficiently assimilate Tl from soil. Alarmingly, this has made dark green leafy vegetables one of the most common sources of Tl exposure. Thallium has been detected in prenatal vitamins, and clinicians should be aware that the neurotoxic metal readily crosses the placenta to the developing fetus.

The human health issue appears to relate predominately to chronic low-dose exposure via air, water and food sources over time, as opposed to acute high-dose exposure. The more neurologically vulnerable populations such as pregnant women, infants and children are of greater concern and warrant more consideration. Particular caution is to be exercised in instances of large amounts of Spinacia and Brassica group vegetables, such as juicing, in the diet. The current culture strongly advocates dark green leafy vegetables as healthy due to their mineral and folate contents, yet the health risks of Tl exposure must be weighed against the benefits. Furthermore, in sensitive populations and those consuming large amounts of Spinacia and Brassica group vegetables, urine levels of Tl may be clinically relevant. Clinicians should be aware of the neurotoxic potential of Tl. Mitigating Tl exposure could benefit human health on the individual and greater community levels. 

Doctor’s Data offers multiple profiles that test toxic metals (such as thallium) and essential element status, which can be assessed in urine, blood, stool and hair. To learn more about these profiles, and which ones may be appropriate for your patients, click here: https://www.doctorsdata.com/toxic-essential-elements/

 

References

Ind J Occup Environ Med (2005)9:53-55 CDC/NIOSH 2016

Peter AL, Viraraghavan T. Thallium: a review of public health and environmental concerns. Environ Int. 2005 May;31(4):493-501.

Public Health Statement Thallium CAS#: 7440-28-0. https://www.atsdr.cdc.gov/ToxProfiles/tp54-c1-b.pdf

Sampling and Analysis of Water Streams Associated with the Development of Marcellus Shale Gas: Final Report http://www.water-research.net/naturalgasPA/pdffiles/MSCommission-Report.pdf. Dec. 31, 2009.

Schwalfenberg, et all. Heavy metal contamination of prenatal vitamins. Toxicology Reports. March 2018. DOI: 10.1016/j.toxrep.2018.02.015

Stoiber, Tasha. Toxic Chemicals May Contaminate Oil Field Wastewater Used to Grow Calif. Crops. https://www.ewg.org/research/toxic-chemicals-may-contaminate-oil-field-wastewater-used-grow-calif-crops#.WYHtV4TyuUk. October26, 2019.

Disclaimer: All information given about health conditions, treatment, products, and dosages are for educational purposes only and do not constitute medical advice.