Doctor's Data Inc

Fatty Acids; Erythrocytes

The typical Western diet contains too many carbohydrates and saturated fats, and is often imbalanced with respect to essential and nonessential fatty acid intake. Erythrocyte fatty acid nutritional testing is used to assess levels of and balance among the essential and non-essential fatty acids required for optimal health and wellness. Essential fatty acids regulate cell membrane integrity, blood pressure and coagulation, lipid levels, immune response, tumor growth and inhibition, and the inflammatory response to injury and infection. Erythrocyte Fatty Acid nutritional testing aids in developing the most efficacious dietary and supplemental treatment program to restore appropriate ratios among fatty acids.
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Turnaround Time

3 to 5 days

Analytes Tested

Click any analyte name for additional clinical information, including reference ranges, specimen collection, stability and rejection criteria.


Analyte CPT ABN Required
Arachidonic acid; RBC 82542 Yes
Dihomo-g-linolenic acid; RBC 82542 Yes
Docosahexaenoic acid; RBC 82542 Yes
Eicosapentaenoic acid; RBC 82542 Yes
Elaidic acid; RBC 82542 Yes
Linoleic acid; RBC 82542 Yes
Oleic acid; RBC 82542 Yes
Palmitelaidic acid; RBC 82542 Yes
Palmitic acid; RBC 82542 Yes
Palmitoleic acid; RBC 82542 Yes
Stearic acid; RBC 82542 Yes

List price applies when filing with insurance or Medicare, or when billing a patient directly.

Prompt payment pricing applies when billing to a physician account or prepayment is received with the test.

Doctor's Data offers profiles containing multiple analytes. *Multiple analytes may be billed under a single CPT code. Many analytes can be ordered individually. Pricing may vary. Click on a specific analyte for more information or read our detailed billing and payment policies.

The CPT codes listed on our website are for informational purposes only. This information is our interpretation of CPT coding requirements and may not necessarily be correct. You are advised to consult the CPT Coding Manual published by the American Medical Association. Doctor's Data, Inc. takes no responsibility for billing errors due to your use of any CPT information from our website.

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This test is useful for

  • ADD/ADHD
  • Alzheimer's Disease
  • Autism Spectrum Disorders
  • Blood Pressure
  • Cardiovascular Health
  • Coagulation
  • Lipid/Lipoprotein Levels
  • Immune Response
  • Inflammatory Response to Injury and Infection
  • Seizure Disorders
  • Tumor Growth and Inhibition

Detailed Information

Fatty acids (FAs) are primarily derived from triglycerides in the food and oils that we consume. Non-essential FAs are also biosynthesized in the body, especially during times when carbohydrate intake exceeds the body's needs for glucose and glycogen repletion. Non-essential FAs are most commonly recognized as an important source of energy, and when caloric intake exceeds expenditure, these FAs are stored in adipose tissue as triglycerides. However, FA metabolism is much more complex and it is well established that appropriate balance among essential and non-essential FAs, as well as avoidance of harmful trans-FAs, is required for optimal health and wellness.

FAs are monocarboxylic acids that may be either saturated (no C=C double bonds) or unsaturated one or more C=C double bonds). Humans make saturated fatty acids and a monounsaturated fatty acid with a double bond at the omega-9 position but do not have the enzymes necessary to introduce a double bond at the omega-3 (ω-3) or omega-6 (ω-6) positions. The essential fatty acids (EFAs) linoleic acid (18:2) and α-linoleic acid (18:3) are polyunsaturated fatty acids (PUFAs) that are precursors of the ω-6 and ω-3 fatty acid series, respectively. The ω-6 and ω-3 FAs compete for desaturase and elongation enzymes that produce longer-chain, more highly unsaturated FAs. The typical Western diet contains an undesirable preponderance of ω-6 fatty acids that impedes elongation and desaturation of ω-3 FAs. FAs derived from EFAs or taken in via diet or supplements are essential components of cell membrane phospholipids, and appropriate membrane fatty acid content is pivotal for optimal membrane fluidity, receptor activity and cellular metabolism. The same FAs eventually give rise to hormone-like substances (eicosanoids) that are involved in the regulation of blood pressure and coagulation, lipid levels, immune response, tumor growth and inhibition, and the inflammatory response to injury and infection, and may play a role in seizure disorders and dementias such as Alzheimer's disease.

Nutritional testing to determine the appropriate balance of membrane phospholipid EFAs is important because the biological effects of the ω-3 and ω-6 FAs metabolites are mediated by their mutual interactions.

This test measures the primary ω-6 and ω-3 PUFAs, and monounsaturated, saturated and trans FAs that are present as constituents of phospholipids in the membranes of erythrocytes. Each FA is reported as a percentage of the total FAs measured and important FA ratios are presented. Commentary is provided for results exceeding reference intervals.

For nutritional testing to address your patients' symptoms, reach out to Doctor's data.

Nutritional

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