Doctor's Data Inc

Plasma Amino Acids

Amino acid (AA) nutritional testing analysis aids in the identification of dietary protein adequacy and amino acid balance, gastrointestinal dysfunctions, forms of protein intolerance, vitamin and mineral deficiencies, renal and hepatic dysfunction, psychiatric abnormalities, susceptibility to inflammatory response and oxidative stress, reduced detoxification capacity and many other inherent and acquired disorders in AA metabolism. Plasma is traditionally used to assess the status of essential AA while urine analysis provides more information regarding AA wasting and aberrant metabolism associated with co-factor insufficiencies.
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Turnaround Time

3 to 5 days

Analytes Tested

Click any analyte name for additional clinical information, including reference ranges, specimen collection, stability and rejection criteria.


Analyte CPT ABN Required
1-Methylhistidine; plasma 82139 No
3-Methylhistidine; plasma 82139 No
A-Amino-n-butyrate; plasma 82139 No
A-Aminoadipate; plasma 82139 No
Alanine; plasma 82139 No
Ammonia; plasma 82139 No
Anserine; plasma 82139 No
Arginine; plasma 82139 No
Asparagine; plasma 82139 No
Aspartic Acid; plasma 82139 No
B-Alanine; plasma 82139 No
B-Aminoisobutyrate; plasma 82139 No
Carnosine; plasma 82139 No
Citrulline; plasma 82139 No
Cystathionine; plasma 82139 No
Cystine; plasma 82139 No
Ethanolamine; plasma 82139 No
G-Aminobutyrate; plasma 82139 No
Glutamic Acid; plasma 82139 No
Glutamine; plasma 82139 No
Glycine; plasma 82139 No
Histidine; plasma 82139 No
Homocystine; plasma 82139 No
Hydroxyproline; plasma 82139 No
Isoleucine; plasma 82139 No
Leucine; plasma 82139 No
Lysine; plasma 82139 No
Met Sulfoxide; plasma 82139 No
Methionine; plasma 82139 No
Ornithine; plasma 82139 No
Phenylalanine; plasma 82139 No
Phosphoethanolamine; plasma 82139 No
Phosphoserine; plasma 82139 No
Proline; plasma 82139 No
Sarcosine; plasma 82139 No
Serine; plasma 82139 No
Taurine; plasma 82139 No
Threonine; plasma 82139 No
Tryptophan; plasma 82139 No
Tyrosine; plasma 82139 No
Urea; plasma 82139 No
Valine; plasma 82139 No

List price applies when filing with insurance or Medicare, or when billing a patient directly.

Prompt payment pricing applies when billing to a physician account or prepayment is received with the test.

Doctor's Data offers profiles containing multiple analytes. *Multiple analytes may be billed under a single CPT code. Many analytes can be ordered individually. Pricing may vary. Click on a specific analyte for more information or read our detailed billing and payment policies.

The CPT codes listed on our website are for informational purposes only. This information is our interpretation of CPT coding requirements and may not necessarily be correct. You are advised to consult the CPT Coding Manual published by the American Medical Association. Doctor's Data, Inc. takes no responsibility for billing errors due to your use of any CPT information from our website.

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Detailed Information

Many individuals have "hidden" impairments in amino acid metabolism that are problematic and often go undiagnosed. These impairments may or may not be expressed as specific symptoms. They may silently increase susceptibility to a degenerative disease or they may be associated with, but not causative for, a disease. Because of the wealth of information provided, it is suggested that a complete amino acid analysis be performed whenever a thorough nutritional testing and a metabolic workup is called for.

Amino acid analysis provides fundamental information about nutrient adequacy, including the quality and quantity of dietary protein, digestive disorders, and vitamin and mineral deficiencies—particularly folic acid, B12, B6 metabolism, zinc and magnesium. In addition, amino acid analysis provides important diagnostic information about hepatic and renal function, availability of precursors of neurotransmitters, detoxification capacity, susceptibility to occlusive arterial disease (homocystine), and many inherent disorders in amino acid metabolism.

The patient's results are presented in a functional format that permits ease of interpretation. A comprehensive summary of "presumptive needs" (such as B6, B12/folate, Mg) and "implied conditions" (such as maldigestion/malabsorption, abnormal gastrointestinal flora, impaired detoxification, oxidative stress) are presented based upon each patient's results. Patient-specific amino acid supplement schedules and user-friendly commentary are provided to simplify nutritional intervention.

Plasma vs. Urine Analysis
Plasma is traditionally used to assess the status of essential AA while urine analysis provides more information regarding AA wasting and aberrant metabolism associated with co-factor insufficiencies.

Plasma amino acid nutritional testing measures what is being transported at the time of sampling. The specimen should be collected after an overnight fast to reduce the influence of dietary protein. Abnormalities are deduced by comparison of measured levels with an established reference range.

The 24-hour urine amino acid analysis has the highest probability of detecting abnormalities if renal function is normal. The 24-hour test indicates what is high and low over the course of a day, reflects blood and tissue amino acid pools, and is not affected by circadian rhythm. Healthy kidneys efficiently conserve essential amino acids. Therefore, urine levels of amino acids decrease first and tend to give an earlier indication of inadequacy than do plasma levels.

A first morning void urine (FMV) amino acid analysis, with results normalized per gram creatinine, provides an alternative when a complete 24-hour collection is not a viable option. The FMV analysis is excellent for identification of marked abnormalities, particularly with respect to gastrointestinal health, inherited disorders in amino acid metabolism and renal function, and can be used for protein challenge testing.

For nutritional testing to address your patients' symptoms, reach out to Doctor's Data.

Nutritional

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