Doctor's Data Inc

Comprehensive Blood Elements

Whole blood metals are the standard for diagnosis of lead, mercury or other metal toxicity or poisoning, and are also used to assess recent or ongoing exposure to potentially toxic elements. Serum elements are used to assess the status of key elements and electrolytes that have important functions in the extracellular fluid compartment of blood. Whole Blood and Serum Elements tests are available separately or as part of the Comprehensive Blood Elements profile.
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Turnaround Time

3 to 5 days

Analytes Tested

Click any analyte name for additional clinical information, including reference ranges, specimen collection, stability and rejection criteria.


Analyte CPT ABN Required
Arsenic; whole blood 82175 Yes
Barium; whole blood 83018 Yes
Cadmium; whole blood 82300 Yes
Calcium (total); serum 82310 No
Calcium; whole blood 82310 Yes
Chromium; whole blood 82495 Yes
Cobalt; whole blood 83018 Yes
Copper; whole blood 82525 Yes
Iron; serum 83540 Yes
Lead; whole blood 83655 Yes
Lithium; whole blood 80178 Yes
Magnesium; serum 83735 No
Magnesium; whole blood 83735 Yes
Manganese; whole blood 83785 Yes
Mercury; whole blood 83825 Yes
Molybdenum; whole blood 83018 Yes
Nickel; whole blood 83885 Yes
Phosphorus (Inorganic); serum 84100 No
Platinum; whole blood 83018 Yes
Potassium; serum 84132 No
Selenium; whole blood 84255 Yes
Sodium; serum 84295 No
Strontium; whole blood 83018 Yes
Thallium; whole blood 83018 Yes
Tungsten; whole blood 83018 Yes
Uranium; whole blood 83018 Yes
Vanadium; whole blood 83018 Yes
Zinc; whole blood 84630 Yes

List price applies when filing with insurance or Medicare, or when billing a patient directly.

Prompt payment pricing applies when billing to a physician account or prepayment is received with the test.

Doctor's Data offers profiles containing multiple analytes. *Multiple analytes may be billed under a single CPT code. Many analytes can be ordered individually. Pricing may vary. Click on a specific analyte for more information or read our detailed billing and payment policies.

The CPT codes listed on our website are for informational purposes only. This information is our interpretation of CPT coding requirements and may not necessarily be correct. You are advised to consult the CPT Coding Manual published by the American Medical Association. Doctor's Data, Inc. takes no responsibility for billing errors due to your use of any CPT information from our website.

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This test is useful for

  • Alopecia
  • Anemia
  • Bone Density
  • Cardiovascular Disease
  • Depression
  • Dermatitis or Poor Wound Healing
  • Detoxification Therapy
  • Fatigue
  • Malabsorption
  • Hypertension
  • Immune Dysfunction
  • Impaired Glucose Tolerance
  • Inflammation
  • Kidney Function
  • Nutritional Deficiencies
  • Parkinson's-like Symptoms
  • Sexual Impotence or Decreased Testosterone Production
  • Vision Problems

Detailed Information

Blood elemental analysis should be performed prior to the initiation of, and intermittingly during, metal detoxification. Toxic metals disrupt essential element metabolism and are antagonistic to some elements such as cadmium to zinc and lead to calcium. Further, commonly utilized metal detoxification agents can cause significantly increased urinary wasting of some essential elements. For example, EDTA has a very high affinity for zinc and manganese, and DMPS results in marked increases in copper excretion. Therefore, appropriate evaluation of essential element status is an integral component of safe and effective metal detoxification therapy. Analysis of toxic elements/metals in whole blood is useful for assessment of recent or ongoing exposure to the toxins, but does not provide accurate information about net retention of toxic metals in the body. For example, blood lead levels peak about five hours after acute exposure and then decrease exponentially with a half-life in blood of about one month. Evaluation and elimination of ongoing exposure to toxic metals is another important component of efficient metal detoxification. Accurate assessment of essential element status in the most appropriate compartment is highly recommended for determination of appropriate supplementation. The absorption, transport and metabolism of essential elements is highly integrated and regulated. Inappropriate supplementation or dietary imbalance of elements can have significant adverse health effects. For example, excess intake of zinc or molybdenum can result in copper deficiency and excess assimilation of manganese can have serious neurotoxic effects that are expressed as Parkinson's-like disease. Whole blood analysis is an excellent test for measuring the levels of both intracellular and extracellular circulating elements. Extracellular elements have functions in serum/plasma or are transported to tissues in serum/plasma associated with specific proteins or albumen. Intracellular elements have very specific functions as obligatory constituents of metalloproteins/enzymes in red blood cells and lymphocytes. The red and white blood cells serve as surrogate cells representative of peripheral cells in general. Some essential elements, such as selenium, are portioned in and have important physiological roles in both the intracellular and extracellular compartments. Likewise, the toxic metal lead is transported in both the fluid and cellular (red blood cells) compartments of blood. Therefore measurement of elements in both blood compartments permits a more complete evaluation of total blood element levels. In contrast, some essential elements/electrolytes such as calcium, sodium, potassium and iron are best assessed in serum because they are transported by serum proteins or have important functions in the extracellular compartment of blood. Also, the differential analysis of some elements, such as magnesium, in both whole blood and serum can provide important clinical information about aberrant metabolism of this extremely important element that is involved in over 300 different intracellular reactions. Blood elemental analysis is available in whole blood, in serum and as a Comprehensive Blood Elements profile which is comprised of both whole blood and serum elements. It is highly recommended that blood and serum specimens be collected after an overnight fast to avoid the acute influence of a meal.

Toxic and Essential Elements

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