Doctor's Data Inc

Comprehensive Stool Analysis

Gastrointestinal complaints are among the most common reasons that patients seek medical care. Symptoms associated with GI disorders include persistent diarrhea, constipation, bloating, indigestion, irritable bowel syndrome and malabsorption. The Comprehensive Stool Analysis can help assess digestive and absorptive functions, the presence of opportunistic pathogens and to monitor the efficacy of therapeutic remediation of GI disorders. Antimicrobial susceptibility testing to prescriptive and natural agents is also performed for appropriate bacterial and fungal species at no additional charge.
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Turnaround Time

6 to 8 days

Analytes Tested

Click any analyte name for additional clinical information, including reference ranges, specimen collection, stability and rejection criteria.

Analyte CPT ABN Required
Acetate; stool 82542 Yes
Additional pathogens culture; stool 87046 No
Bacteriology culture, aerobic; stool 87045 No
Butyrate; stool 82542 Yes
Calprotectin; stool 83993 Yes
Carbohydrates; stool * No
Elastase; stool 82656 No
Fat Stain; stool 89125 No
Lactoferrin; stool 83631 No
Lysozyme; stool 85549 Yes
Mucus; stool * No
Muscle Fibers; stool 89160 No
Occult Blood; stool 82272 Yes
Propionate; stool 82542 Yes
Red Blood Cells; stool * No
Valerate; stool 82542 Yes
Vegetable Fibers; stool 89160 No
White Blood Cells; stool * No
Yeast culture; stool 87102 No
ph; stool 83986 No
sIgA; stool 83520 Yes

List price applies when filing with insurance or Medicare, or when billing a patient directly.

Prompt payment pricing applies when billing to a physician account or prepayment is received with the test.

Doctor's Data offers profiles containing multiple analytes. *Multiple analytes may be billed under a single CPT code. Many analytes can be ordered individually. Pricing may vary. Click on a specific analyte for more information or read our detailed billing and payment policies.

The CPT codes listed on our website are for informational purposes only. This information is our interpretation of CPT coding requirements and may not necessarily be correct. You are advised to consult the CPT Coding Manual published by the American Medical Association. Doctor's Data, Inc. takes no responsibility for billing errors due to your use of any CPT information from our website.

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This test is useful for

  • Gastrointestinal Symptoms
  • Autoimmune Disease
  • Joint Pain
  • IBD/IBS
  • Inflammation
  • Food Sensitivities
  • Nutritional Deficiencies
  • Skin Conditions (Atopic Dermatitis)

Detailed Information

The Comprehensive Stool Analysis is an invaluable non-invasive diagnostic assessment that permits practitioners to objectively evaluate the status of beneficial and imbalanced commensal bacteria including Clostridium species, pathogenic bacteria and yeast/fungus. Precise identification of pathogenic species and susceptibility testing greatly facilitates selection of the most appropriate pharmaceutical or natural treatment agents.

Important information regarding the efficiency of digestion and absorption can be gleaned from the measurement of the fecal levels of elastase (pancreatic exocrine sufficiency), fat, muscle and vegetable fibers, and carbohydrates.

Inflammation can significantly increase intestinal permeability and compromise assimilation of nutrients. The extent of inflammation, whether caused by pathogens or inflammatory bowel disease (IBD), can be assessed and monitored by examination of the levels of biomarkers such as lysozyme, lactoferrin, white blood cells and mucus. These markers can be used to differentiate between inflammation associated with potentially life-threatening inflammatory bowel disease (IBD), which requires lifelong treatment, and less severe inflammation that can be associated with irritable bowel syndrome (IBS) which is frequently due to the presence of enteroinvasive pathogens. Lactoferrin is only markedly elevated prior to and during the active phases of IBD, but not with IBS. Monitoring fecal lactoferrin levels in patients with IBD can therefore facilitate timely treatment of IBD, and the test can be ordered separately. Since the vast majority of secretory IgA (sIgA) is normally present in the GI tract, where it prevents binding of pathogens and antigens to the mucosal membrane, it is essential to know the status of sIgA in the gut. sIgA is the only bona fide marker of humoral immune status in the GI tract.

Cornerstones of good health include proper digestion of food, assimilation of nutrients, exclusion of pathogens and timely elimination of waste. To obtain benefits from food that is consumed, nutrients must be appropriately digested and then efficiently absorbed into portal circulation. Microbes, larger-sized particles of fiber, and undigested foodstuffs should remain within the intestinal lumen. Poor digestion and malabsorption of vital nutrients can contribute to degenerative diseases, compromised immune status and nutritional deficiencies. Impairment of the highly specific nutrient uptake processes, or compromised GI barrier function, as in "leaky gut syndrome," can result from a number of causes including:


•  Low gastric acid production
•  Chronic maldigestion
•  Food allergen impact on bowel absorptive surfaces
•  Bacterial overgrowth or imbalances (dysbiosis)
•  Pathogenic bacteria, yeast or parasites and related toxic irritants
•  The use of NSAIDs and antibiotics

Impairment of intestinal functions can contribute to the development of food allergies, systemic illnesses, autoimmune disease, and toxic overload from substances that are usually kept in the confines of the bowel for elimination. Efficient remediation of GI dysfunctions incorporates a comprehensive guided approach that should include consideration of elimination of pathogens and exposure to irritants, supplementation of hydrochloric acid, pancreatic enzymes and pre- and probiotics, and repair of the mucosal barrier.

The Comprehensive Stool Analysis does not include analysis for parasites. For assessment of the presence for parasites, consider the Comprehensive Stool Analysis with Parasitology.

Clinical Microbiology

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