Doctor's Data Inc

Stool Toxic Metals

Analysis of elements in stool provides a means to assess oral exposure, and to a lesser extent endogenous detoxification of potentially toxic metals. For several toxic elements such as mercury, cadmium, lead, antimony and uranium, biliary excretion of metals into feces is a primary natural route of elimination from the body. Specimen collection is convenient for the patient and only requires a single-step procedure. Elements are measured by ICP-MS and expressed on a dry weight basis to eliminate variability related to water content of the specimen. To provide guidance in interpretation of results, patient values are plotted graphically with respect to percentile distribution of the population base.
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Turnaround Time

3 to 5 days

Analytes Tested

Click any analyte name for additional clinical information, including reference ranges, specimen collection, stability and rejection criteria.


Analyte CPT ABN Required
Antimony; stool 83018 Yes
Arsenic; stool 82175 Yes
Beryllium; stool * Yes
Bismuth; stool * Yes
Cadmium; stool 82300 Yes
Cesium; stool * Yes
Copper; stool 82525 Yes
Gadolinium; stool * Yes
Lead; stool 83655 Yes
Manganese; stool 83785 Yes
Mercury; stool 83825 Yes
Nickel; stool 83885 Yes
Platinum; stool * Yes
Thallium; stool * Yes
Tungsten; stool * Yes
Uranium; stool * Yes

List price applies when filing with insurance or Medicare, or when billing a patient directly.

Prompt payment pricing applies when billing to a physician account or prepayment is received with the test.

Doctor's Data offers profiles containing multiple analytes. *Multiple analytes may be billed under a single CPT code. Many analytes can be ordered individually. Pricing may vary. Click on a specific analyte for more information or read our detailed billing and payment policies.

The CPT codes listed on our website are for informational purposes only. This information is our interpretation of CPT coding requirements and may not necessarily be correct. You are advised to consult the CPT Coding Manual published by the American Medical Association. Doctor's Data, Inc. takes no responsibility for billing errors due to your use of any CPT information from our website.

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This test is useful for

  • Dietary Exposure to Toxic Elements
  • Mercury Exposure from Dental Amalgams

Detailed Information

Analysis of elements in stool provides a comprehensive evaluation of dietary exposure, and to a lesser extent endogenous detoxification of potentially toxic metals. A primary objective of preventive medicine is avoidance or removal of exposure to toxic substances. The results of stool elemental analysis can help identify and eliminate dietary exposure to toxic metals. The rate of oral absorption of toxic metals varies considerably among elements, and among subspecies of a particular element. Orally, the percent absorption of elemental nickel, cadmium and lead is usually quite low, but varies significantly in part due to the relative abundance of antagonistic essential elements in the diet. That is particularly evident for lead and calcium, and cadmium and zinc. Chronic, low-level assimilation of the toxic metals may result in accumulation in the body. Since this test reflects both oral exposure and biliary excretion of metals, overt clinical associations are not directly implied.

Studies performed at Doctor’s Data demonstrate that the stool mercury (Hg) content and number of amalgam surfaces are highly correlated. It also clear that stool Hg levels for people with dental amalgams are remarkably similar from day to day. Therefore, people with several amalgams in place will typically have higher concentrations of stool Hg than people without amalgams. A direct association between stool Hg levels and health has not been established, but a land mark study of amalgam placement in monkeys indicated there was an associated induction of co-resistance to both Hg and antibiotics by pathogenic bacteria in the gastrointestinal tract, particularly for species in the Enterobacteriaceae family. Such was also reported for miners exposed to elemental Hg while working in gold mines.

For several toxic elements such as mercury, cadmium, lead, and antimony, biliary excretion of metals into stool is a primary natural route of elimination from the body. The process by which the body eliminates the sulfhydryl reactive metals is through the formation of metal-glutathione complexes that are excreted into the bile and urine. Elemental analysis of stool specimens may provide a tool to monitor the efficacy of natural detoxification of metals in infants or patients who are on very limited or “clean” diets that do not contain contaminated solid foods.

The unique Toxic Metals; Stool Test evaluates levels of thallium and gadolinium which are of increasing potential concern, plus 14 other potentially toxic elements. Specimen collection is convenient for the patient and only requires a single-step procedure. Sixteen elements are measured by ICP-MS and expressed on a dry weight basis to eliminate variability related to water content of the specimen.

Toxic and Essential Elements

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