Doctor's Data Inc

Red Blood Cell (RBC) Elements

Red blood cell (RBC) elements tests are used to assess the status of essential elements with important intracellular functions, such as magnesium, copper and zinc. Deficiencies or excesses of these essential elements affect numerous metabolic processes. RBC element analysis is also useful for the assessment of ongoing or recent exposure to specific toxic metals, such as arsenic, cadmium, lead, methylmercury and thallium, that accumulate preferentially in erythrocytes.
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Turnaround Time

3 to 5 days

Analytes Tested

Click any analyte name for additional clinical information, including reference ranges, specimen collection, stability and rejection criteria.


Analyte CPT ABN Required
Arsenic; RBC 82175 Yes
Boron; RBC 83018 Yes
Cadmium; RBC 82300 Yes
Calcium; RBC 82310 Yes
Cesium; RBC 83018 Yes
Chromium; RBC 82495 Yes
Copper; RBC 82525 Yes
Iron; RBC 83540 Yes
Lead; RBC 83655 Yes
Magnesium; RBC 83735 Yes
Manganese; RBC 83785 Yes
Mercury; RBC 83825 Yes
Molybdenum; RBC 83018 Yes
Phosphorus; RBC 84999 Yes
Potassium; RBC 84999 Yes
Selenium; RBC 84255 Yes
Thallium; RBC 83018 Yes
Zinc; RBC 84630 Yes

List price applies when filing with insurance or Medicare, or when billing a patient directly.

Prompt payment pricing applies when billing to a physician account or prepayment is received with the test.

Doctor's Data offers profiles containing multiple analytes. *Multiple analytes may be billed under a single CPT code. Many analytes can be ordered individually. Pricing may vary. Click on a specific analyte for more information or read our detailed billing and payment policies.

The CPT codes listed on our website are for informational purposes only. This information is our interpretation of CPT coding requirements and may not necessarily be correct. You are advised to consult the CPT Coding Manual published by the American Medical Association. Doctor's Data, Inc. takes no responsibility for billing errors due to your use of any CPT information from our website.

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This test is useful for

  • Alopecia
  • Anemia
  • Bone Density
  • Cardiovascular Disease
  • Depression
  • Dermatitis or Poor Wound Healing
  • Detoxification Therapy
  • Fatigue
  • Gastrointestinal Symptoms
  • Hypertension
  • Inflammation
  • Immune Function
  • Impaired Glucose Tolerance
  • Kidney Function
  • Nutritional Deficiencies
  • Parkinson's-like Symptoms
  • Sexual Impotence or Decreased Testosterone Production
  • Vision Problems

Detailed Information

Red blood cell (RBC) analysis is an invaluable method for assessing insufficiency or excess of elements that have important functions within cells or on blood cell membranes. An important feature of this analysis is that the cells are not washed, because this would result in partial loss of some important elements, such as calcium, that bind to the plasma membrane.
RBC element levels are very useful for:

•  Cardiotonic influences (magnesium, potassium) •  Anti-inflammatory processes (selenium, copper, zinc) •  Anemia (copper, iron) •  Immunological function (zinc, copper, magnesium) •  Glucose tolerance (chromium, manganese and possibly vanadium)
Disorders specifically associated with zinc deficiency are also addressed by this analysis. These disorders include loss of visual acuity, dysgeusia, dermatitis and poor wound healing, alopecia, amino acid malabsorption, sexual impotence, decreased production of testosterone, depressed immune function and growth retardation.
Accurate assessment of essential element status is highly recommended for the determination of appropriate supplementation. The absorption, transport and metabolism of essential elements is highly integrated and regulated. Inappropriate supplementation or dietary imbalance of elements can have significant adverse health effects. For example, excess intake of zinc or molybdenum can result in copper deficiency and, although essential, excess retention of manganese can have serious neurotoxic effects.
RBC element analysis is also useful for the assessment of ongoing or very recent exposure to specific toxic elements that accumulate preferentially in erythrocytes. These toxic elements include arsenic, cadmium, lead, methylmercury and thallium. It is important to keep in mind that elevated levels of the toxic elements in these cells reflect only recent or ongoing exposure and do not provide information about the net retention of the metals in the body.
RBC element analysis should be performed prior to and intermittently throughout the course of detoxification or chelation therapy. Monitoring essential element status is necessary to identify needs for and effectiveness of supplementation. Replacement and maintenance of adequate levels of essential nutrients can markedly reduce the apparent adverse "side effects" associated with the use of detoxification agents and the general effects of mobilization of toxic elements. It is important to note that some diseases are associated with abnormal levels of blood cell elements that could be misleading with respect to nutritional status. For example, blood cell copper can be temporarily elevated during inflammatory response while liver levels are not.

Toxic and Essential Elements

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