Doctor's Data Inc

GI Pathogen Profile, multiplex PCR

Viruses, parasites, and bacteria—now you can receive 22 results with 1 test.

Overlapping symptoms—compounded by the lack of testing methods that could identify a full range of viruses, parasites, and bacteria—have historically made GI infections difficult to diagnose. The GI Pathogen Profile, an FDA-cleared molecular test, uses the FilmArray multiplex PCR system to identify 22 viruses, parasites, and bacteria with up to 98.5% overall sensitivity and 99.3% overall specificity.

Get to diagnosis—and targeted treatment—faster.

Most results can be provided within one business day of receiving a sample. As a result, you can begin targeted treatment immediately, for greater therapeutic efficacy and reduced risk of complications and side effects associated with incorrect treatment or unwarranted antimicrobial administration.

Use the GI Pathogen Profile as a stand-alone test, or as a complement to our Comprehensive Stool Analysis, to test for the presence of viral infections or to differentiate between possible diarrheagenic strains of E. coli.
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Turnaround Time

0 to 1 days

Analytes Tested

Click any analyte name for additional clinical information, including reference ranges, specimen collection, stability and rejection criteria.

Analyte CPT ABN Required
Adenovirus F40&41 87507 No
Astrovirus * No
Campylobacter (jejuni, coli and upsaliensis) * No
Clostridium difficile (Toxin A&B) * No
Cryptosporidium * No
Cyclospora cayetanensis * No
E. coli O157 * No
Entamoeba histolytica * No
Enteroaggregative E. coli (EAEC) * No
Enteropathogenic E. coli (EPEC) * No
Enterotoxigenic E. coli (ETEC) lt&st * No
Giardia duodenalis * No
Norovirus GI&GII * No
Plesiomonas shigelloides * No
Rotavirus A * No
Salmonella * No
Sapovirus (I, II, IV and V) * No
Shiga-like toxin-producing E. coli (STEC) stx1&stx2 * No
Shigella&Enteroinvasive E. coli (EIEC) * No
Vibrio (parahaemolyticus, vulnificus and cholerae) * No
Vibrio cholerae * No
Yersinia enterocolitica * No

List price applies when filing with insurance or Medicare, or when billing a patient directly.

Prompt payment pricing applies when billing to a physician account or prepayment is received with the test.

Doctor's Data offers profiles containing multiple analytes. *Multiple analytes may be billed under a single CPT code. Many analytes can be ordered individually. Pricing may vary. Click on a specific analyte for more information or read our detailed billing and payment policies.

The CPT codes listed on our website are for informational purposes only. This information is our interpretation of CPT coding requirements and may not necessarily be correct. You are advised to consult the CPT Coding Manual published by the American Medical Association. Doctor's Data, Inc. takes no responsibility for billing errors due to your use of any CPT information from our website.

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This test is useful for

  • Chronic or acute diarrhea
  • Bloody stool
  • Travelers diarrhea
  • Abdominal pain
  • Fever & vomiting
  • Immuno-compromised patients
  • Geriatric patients
  • Chronic disease patients (heart disease, aortic grafts, diabetes, chronic renal disease)
  • Observed cluster or suspected outbreak of diarrheal illness

Detailed Information

The GI Pathogen Profile, using the FilmArray multiplex PCR system, tests for 22 Viruses, parasites, and bacteria, and offers new opportunities for the rapid, accurate diagnosis and prompt treatment of diarrheal illnesses which can improve patient outcomes and clinical success.

While bacteria and parasites are the primary cause of food & water-borne diarrheal illness (48 million infections/year), the vast majority of acute diarrheal illness is caused not by bacteria or parasites, but by viral infections. In fact, Norovirus is the primary gastrointestinal infection occurring in the United States. Even though testing for pathogenic bacteria and parasite is commonly available, there has been limited availability of viral testing until recently.

Acute gastroenteritis may contribute to patient morbidity and even mortality, if the illness progresses to severe dehydration. Also, the identification of reportable diseases is imperative to prevent large outbreaks, especially for highly contagious or food-borne illnesses, and many gastrointestinal illnesses have very similar clinical presentations.

If your patient has diarrheal illness, you need accurate results quickly. Most GI Pathogen Profile results can be provided within one business day of sample receipt with up to 98.5% overall sensitivity and 99.3% overall specificity. As a result, you can begin targeted treatment immediately, for greater therapeutic efficacy and reduced risk of complications & side effects associated with incorrect treatment or unwarranted antimicrobial administration.

Rapid diagnosis allows for better treatment decisions, as antimicrobial agents have no effect on viral illness, and the indiscriminate use of antibiotics may increase bacterial resistance. Certain pathogenic bacterial and parasitic infections may require antimicrobial treatment, while other infections warrant rehydration and supportive therapies. Knowing the difference allows the treating physician to practice good antimicrobial stewardship.

Use the GI Pathogen Profile as a stand-alone test, or as a complement to our Comprehensive Stool Analysis, to test for the presence of viral infections or to differentiate between possible diarrheagenic strains of E. coli.

Clinical Microbiology

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