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The Estrobolome: How Gut Dysbiosis and Liver Detoxification Shape Estrogen Balance

Presented by Dan Kalish, DC | July 7, 2026 at 12 PM Pacific

Estrogen balance is shaped by more than hormone production. It also depends on gut microbiome health, liver detoxification, and the body's ability to properly eliminate or recycle estrogen.

This class explains how the estrobolome influences estrogen metabolism, how Phase II liver detoxification prepares estrogen for excretion, and how gut dysbiosis and beta-glucuronidase activity can lead to excess estrogen recycling and hormone-related symptoms.

Learning Objectives:

  • Understand the role of the estrobolome in estrogen regulation.
  • Map the connection between liver detoxification, gut excretion, and estrogen recycling.
  • Learn how beta-glucuronidase can reactivate estrogen for reabsorption.
  • Recognize how gut dysbiosis may contribute to estrogen dominance.
  • Identify key stool and hormone biomarkers related to estrogen clearance

Register here:

12:00 PM PST

The Hormone-Mitochondria Axis: Linking Endocrinology to Cellular Bioenergetics

Presented by Laura Neville, ND | August 5, 2026 at 12 PM Pacific

Learning Objectives:

  • Explain the role of mitochondria in cellular energy production and endocrine function.
  • Describe how hormones regulate mitochondrial biogenesis, metabolism, and oxidative stress.
  • Recognize clinical conditions associated with hormone-driven mitochondrial dysfunction.
  • Identify laboratory and functional assessments that may aid in evaluating mitochondrial health.
  • Apply evidence-informed strategies to support mitochondrial function and optimize metabolic and hormonal health.

Register here:

12:00 PM PST

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